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Advanced Research Insights MOTS-cs nuclear translocation activates genes for fatty acid oxidation (e.g., MCAD) and folate metabolism, explaining osteoporosis protection in models

Castleton, P

The highest risk appears to be in patients with type 2 diabetes who have established diabetic retinopathy at the time of treatment initiation, particularly when aggressive glycemic targets are pursued rapidly without appropriate ophthalmologic monitoring

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