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Mechanistically, CB-839 elevates the levels of intracellular ROS, enhances the movement of Nrf2 into the nucleus, leading to an increase in uridine phosphorylase 1 (UPP1) mRNA expression

Absolute bioavailability following intramuscular administration ranged from 14 to 19% in rats and 45 to 51% in beagle dogs

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This preservative extends usability for multiple withdrawals under sterile conditions