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While these studies demonstrate compelling evidence of natural compounds efficacy, limitations remain, including insufficient clarity on dosing duration in certain investigations, such as those by Qi et al

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04.02) with 60 or 100 oil immersion objective lenses (NA 1.35 or 1.40, respectively) or a confocal microscope LSM980 (Zeiss) equipped with the PlanApo 63 /1.4 oil lens (Zeiss)

( A ) and ( B ) ROS measured using the MitoSOX assay in RKO and DLD-1 cells, treated as indicated