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Persistent senescent cells have been associated with aging or age-related diseases via secretion of proinflammatory cytokines that alter the tissue microenvironment or modify the function of normal cells (Baker et al., 2011)

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10.3389/fphar.2022.1038285 38 Klliker-FrersR.UdovinL.Otero-LosadaM.KobiecT.HerreraM