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In the present study, aortic PWV was not reduced by CIT and CIT+GSH supplementations

Rectal absorption could be also compared to transdermal (through the skin) absorption due to the anatomy of the rectum

RNA was reverse transcribed using High-capacity RNA-cDNA reverse transcription Kit on a Mini Amp Plus Thermal Cycler (Thermo Fisher, Waltham, MA), and qRT-PCR was performed using TaqMan Fast Advanced master mix on a CFX96 Real-Time System (Bio-Rad, Hercules, CA)

Overall, long-term hyperglycemia causes vascular and nerve damage, affecting blood supply and nerve conduction in the penis, ultimately impacting erectile function and fertility