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But that peripheral-only action means it does not suppress appetite, does not change energy expenditure through central pathways, and does not produce the dramatic caloric deficits that GLP-1 agonists like semaglutide or tirzepatide create

Targeting Free Radicals in Oxidative Stress-Related Human Diseases

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doi: 10.1155/2020/8844280 108 GuillinO

The cytoplasmic ADNP is also known to interact with cytoskeletal microtubules (MTs) and MT-associated proteins, including Tau and MT end-binding proteins (EB1 and EB3), related to ASD pathology [293]