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That figure came from an assay-specific in-vitro spine-density assay (picomolar Dihexa versus nanomolar BDNF) and does not mean Dihexa is millions of times more effective in a living brain

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Clinical Update 3/01/2024 Sweeteners and Bladder Pain If you suffer from bladder pain, find out which sweeteners have been associated with increased pain in our article about sugar substitutes

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Formulations are not standardised concentrations vary by compounding pharmacy, which is one reason cross-clinic comparisons and published timelines are unreliable