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In a meta-analysis involving 25 controlled trials and 791 individuals, SAMe offered statistically significant support for positive mood believed to be due to its support for neurotransmitter monoamine synthesis and function, including dopamine and serotonin

Dissociated TXNIP combines with and activates the NLRP3 inflammasome to induce IL-1 expression in a NLRP3-ASC-caspase-1-dependent manner, thus causing inflammatory reactions

A new weight loss medication helps patients keep weight off and supports healthy lifestyle changes

Despite their promising results, the studies assessing these treatment modalities are often limited by study design, sample size, outcome assessment heterogeneity, and paucity of data regarding their safety profiles

West Sussex, UK: IFT Press/Wiley-Blackwell