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Possible Side Effects of LDN While many children tolerate LDN well, some may experience mild side effects, including: Sleep disturbances, such as vivid dreams or trouble falling asleep Gastrointestinal problems like nausea or stomach discomfort Temporary fatigue or mild headaches If any side effects occur, they are often temporary and may lessen as the body adjusts

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however, no dose adjustments are needed based on renal function