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Because cobalamin in normally absorbed from food through the gastrointestinal tract, chronic diseases that adversely affect the ability of the intestines to absorb nutrients (inflammatory bowel disease is an excellent example) can lead to cobalamin deficiency

The most important part of the intestinal mucosal barrier is the intestinal mucosal mechanical barrier

Strategies that help throughout treatment include eating smaller meals, avoiding fatty foods, staying hydrated, and eating slowly

Anticonvulsants like Topamax (topiramate) treat binge eating disorder (BED) by dialing down the brain's overactivity, which can reduce impulsive behavior linked to overeating