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The SURPASS studies showed promising effects on weight loss

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However, the mechanistic rationale for combining these agents is sound and warrants further investigation

This shift is driven primarily by hormonal changes, specifically the decrease in estrogen, Catherine Metzgar, PhD, RD, director of coaching operations at Virta Health, told Flow Space

It says the healthcare team should monitor response during the first weeks of therapy and adjust guidance based on individual tolerability, schedule, and comorbidities rather than applying one blanket rule to everyone