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These include CTLA-4 mediated interference with antigen-presenting cell function to limit costimulatory signals [113], the secretion of anti-inflammatory cytokines that directly inhibit Th2 and Th17 proliferation and effector functions, and the constitutive expression of high CD25 levels, enabling competitive consumption of IL-2 and the restriction of effector T-cell expansion [114]

to review the association between polymorphism of the GSTP1 gene and various diseases

M., Wen, J., Guy, C., Long, L., Dhungana, Y., Rankin, S., Pelletier, S., Vogel, P., Wang, H., Peng, J., Guan, K

Annals of Thoracic Surgery 120(2):401-410, 2025

Penman, C