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The only fat dissolving injection that has been approved by the FDA is Kybella (deoxycholic acid) for limited use (the chin)
Compared to other medications for obesity, orlistat produces the least weight loss (2.6 kg) (Khera R et al, JAMA 2016;315(22):24242434)
The mechanism appears to involve increased fat metabolism and reduced fat accumulation, potentially through AMPK activation
The timing was striking: Novo Nordisks FDA-approved Wegovy pill had launched barely a month earlier on January 5, with a starting cash price of $149 per month and $199 per month thereafter
February 8, 2021
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