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This is often your body's way of "recalibrating" to its new weight

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Human Equivalent Dose Calculations Using standard conversion formulas accounting for body surface area differences between species, a rat oral dose of 0.0045 mg/lb translates to approximately 0.00073 mg/lb in humans, yielding roughly 0.112 mg/day for a 154-pound person

Ahishali E, Demir K, Ahishali B, Akyuz F, Pinarbasi B, Poturoglu S, Ibrisim D, Gulluoglu M, Ozdil S, Besisik F, Kaymakoglu S, Boztas G, Cakaloglu Y, Mungan Z, Canberk Y, Okten A (2010) Electron microscopic findings in non-alcoholic fatty liver disease: is there a difference between hepatosteatosis and steatohepatitis