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The newest versions of these medications have received FDA approval since 2017 to treat diabetes (for example, Ozempic, Rybelsus, and Mounjaro) and obesity (Wegovy and Zepbound)

[7] But here is the critical distinction I want you to sit with: These drugs are pharmacologically suppressing appetite

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Identify gaps in the literature and ongoing research directions Key gaps include a lack of large, controlled clinical trials, unclear optimal dosing and delivery for reproductive targets, limited long-term safety data for systemic use, and few mechanistic human studies linking molecular changes to fertility outcomes