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Beyond their islet effects, incretins exert pleiotropic actions on the brain (appetite and satiety regulation), gastrointestinal tract (delayed gastric emptying), adipose tissue (lipolysis modulation), and liver (inhibition of hepatic glucose output) (13)

Some weight loss clinics include B12 injections as part of their weight management programs, often in combination with other treatments such as a healthy diet and exercise

Sugihara et al., 1987

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