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Patients who have a BMI over 27 with any weight related disease such as high blood pressure, high cholesterol, PCOS, cardiac conditions, may be eligible for obesity medications

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Clinical studies suggest that Mounjaro may offer greater weight loss benefits than Ozempic due to its dual mechanism of action

however, administration of retatrutide at higher doses significantly reduced circulating FGF21 levels, suggesting that retatrutide efficacy in MASLD is unlikely to be attributable to increased FGF21 levels

A meta-analysis conducted in 20211 disclosed a reduction of allcause mortality by 12 percent