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Its use can lead to bans in professional and collegiate sports

In an eight-week pilot study on 42 people, ondansetron combined with fluoxetine decreased OCD symptoms when compared to the placebo [17]

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Inducers of CYP3A4 The concomitant use of hydrocodone bitartrate and acetaminophen tablets and CYP3A4 inducers, such as rifampin, carbamazepine, and phenytoin, can decrease the plasma concentration of hydrocodone (see CLINICAL PHARMACOLOGY), resulting in decreased efficacy or onset of a withdrawal syndrome in patients who have developed physical dependence to hydrocodone (see WARNINGS)