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Salidroside exerts neuroprotective properties by inhibiting A-induced ferroptosis in AD mouse neurons, and its mechanism is related to Nrf2 activation and the promotion of downstream NQO1, HO-1, and GPX4 protein expression

Unlike hormone replacement therapy (HRT), which carries its own risk-benefit profile, GLP-1 compounds work through the appetite and metabolic regulatory system rather than replacing declining estrogen

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The MTHFR enzyme is responsible for converting folate into its active form, 5-methyltetrahydrofolate