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Both Pfizer and Moderna have developed bivalent vaccines containing ancestral SARS-CoV-2 and an Omicron variant

Removal of SnCs by administration of UBX0101(a compound inducing apoptosis in SnCs) in transgenic mice with anterior cruciate ligament transection (ACLT)-induced OA, inhibited cartilage erosion, reduced pain, and decreased inflammatory markers such as mmp13 and il1 , and enhanced the number of ki-67-positive synovial fibroblasts (184)

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Animal studies have produced interesting findings involving muscle, tendon, ligament, bone, and gastrointestinal tissue