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The single dose, short (1 h) observation period, and lack of placebo arm are limitations in this proof-of-concept study and provide direction for follow-up studies

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1.12 Hashimotos thyroiditis and endogenous factors In addition to external exposures, inherent biological characteristicssuch as sex, hormonal changes, and physiological statesfurther shape the risk and clinical expression of HT

doi: 10.1016/j.celrep.2022.111381 201 WangSWangJMengXYangSWuLChenKet al

doi: 10.1021/acs.chemrev.7b00719 4 BashirS.BandayM.QadriO.BashirA.HilalN.RaderS.et al