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GHK-Cu drives collagen synthesis and wound healing through copper chelation

In contrast to rAmy, Cagri primarily engages the CTR in a bypass conformation, equivalent to that observed when bound to AMYRs, with 85% of particles in the final particle stack stabilised in this conformation (Fig

Angiogenesis & Vascularity: Studied in relation to new blood vessel formation (angiogenesis) and vascular endothelial growth factors, essential for nutrient delivery to damaged tissues

Gonadorelin, a synthetic GnRH, works one step downstream by directly stimulating the pituitary to secrete LH and FSH

Full names for all the enzymes and substrates are given in Additional File 1