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Goldman et al., 1996

Journal of Allergy and Clinical Immunology 136:17081709

Standard clinical practice uses one agent at a time, optimized for individual tolerance and response

[1] [7] Additionally, because glucagon promotes glycogenolysis and gluconeogenesis, there is a theoretical concern regarding glucose management in people with type 2 diabetes, although the GLP-1 and GIP components appear to counterbalance this effect in practice