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The ubiquitin-proteasome system, which functions as your cells quality control mechanism for clearing damaged and misfolded proteins, also receives enhancement from GHK-Cu through 41 upregulated genes

A recent study suggested that GPX4 is a substrate of tripartite motif containing 21 (TRIM21) and can be degraded by TRIM21-mediated ubiquitination, suggesting that inhibiting TRIM21 attenuates ferroptosis

doi:10.1016/j.cct.2023.107176 204