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46 In contrast to the studies supporting the positive impact of GLP-1 RAs, some findings challenge the notion that these agonists consistently enhance cognitive function in various populations

Subgroup analyses identified consistent treatment effects across different groups, with no significant heterogeneity observed by diabetes status for most outcomes

Vitamin B12 Deficiencies and Medications About 10% of the population appears to have normal serum B12, however, their bioavailable B12 is reduced

Over time, the heart muscle eventually fails leading to the development of heart failure and 500,000 patients are diagnosed annually in the United States with heart failure