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In addition, TMAO may accelerate the process of atherosclerosis and increase the risk of cardiovascular diseases through mechanisms such as promoting inflammation, increasing the expression of scavenger receptors, inhibiting reverse cholesterol transport, and enhancing vascular calcification (Luo et al., 2024)

Various factors contribute to oligodendrocyte and myelin damage, resulting in the release of stored iron into the extracellular space, which is taken up by microglia/macrophages

A prospective study of serum metabolites and glioma risk