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The most prevalent symptoms of vitamin B12 deficiency are neurologic, such as paraesthesia in hands and feet, muscle cramps, dizziness, cognitive disturbances, ataxia, and erectile dysfunction, as well as fatigue, psychiatric symptoms like depression, and macrocytic anaemia." Even if a person gets enough vitamin B12 in their diet, some underlying health conditions can affect the absorption of vitamin B12 in the gut

Also, although there was a trend toward lower muscle cell fats when combining the NNMT-inhibiting compound with exercise, the decline was not significant