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Model building For the Fab1-CCR8 complex, the AlphaFold structure of human CCR8 (AlphaFoldDB: P51685), the light chain of the Fab crystal structure of transglutaminase 2-specific autoantibody 693-10-B06 74 , and the heavy chain of the Fab NA884 crystal structure 75 were docked as a rigid body into the cryo-EM map by UCSF Chimera 76

doi:10.1016/j.brainres.2010.11.013 McCall KD, Holliday D, Dickerson E, Wallace B, Schwartz AL, Schwartz C, Lewis CJ, Kohn LD, Schwartz FL (2010) Phenylmethimazole blocks palmitate-mediated induction of inflammatory cytokine pathways in 3T3L1 adipocytes and RAW 264.7 macrophages