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There is a theoretical --- though as yet unproven in humans --- risk that long-term or high-dose use could stimulate growth in existing malignant or pre-malignant cells

M., & Dyken, M

Thursday: right thigh

Cells were maintained in a humidified environment of 5% CO 2 at 37 C, cultured until an optical confluence of 75-100%, detached with 0.05% trypsin-EDTA 1 (25300-054, Invitrogen, Thermo Fisher Scientific, Waltham, Massachusetts, USA), at 37 C for approximately 5 min, and split to new plates according to the experimental procedures

DSIP has stress-protective and adaptogen activity, normalizing brain metabolism in cases of drug addiction (amphetamine), stress, and stroke [6, 7, 8]