The etiology of HIT is primarily related to genetic polymorphisms of DAO or HNMT, diseases associated with DAO or HNMT deficiency, dysbacteriosis, drugs that inhibit DAO activity, foods rich in histamine, foods that inhibit DAO, and foods that promote histamine release
According to the criteria adopted in these guidelines, subjects with FH and without other major risk factors are considered high-risk patients, while those with FH and ASCVD or other major risk factors are considered very high-risk patients, which implies a recommendation to achieve specific treatment goals ( 10 years, the target LDL-C concentration should be 500 mg/dl) and an increased rate of atherosclerosis development (tendon and skin xanthomata below 10 years of age) and significantly increased cardiovascular risk [9, 265]
Bibcode:1988FEBSL.238..343M
In most cases, discomfort is temporary and improves with proper dosing pace, nutrition, and movement
These changes help your body stay strong as it adjusts