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Yes, most compounded semaglutide injections require refrigeration at 28C (3646F) until use, though storage requirements vary by formulation

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If seizures are worse or not the same after starting this drug

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Meanwhile, clinical trials have pointed to GLP-1 agonist benefits in other indications, including chronic kidney disease, metabolic dysfunction-associated steatohepatitis (MASH), Parkinsons disease, Alzheimers, and addiction