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It can also be deaminated by nicotinamide deamidase (ND) produced by gut microflora to form NA
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Endoplasmic reticulum stress: A key player in human disease
10.1152/ajplung.2001.281.1.L183 210
UV exposure induces the production of ROS, which subsequently activate the NF-B and MAPK signaling pathways, leading to increased transcription of pro-inflammatory cytokines (IL-1, TNF-, IL-6 and COX-2) and MMP-1, both of which contribute to inflammation and collagen degradation
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