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It is approved for chorea associated with Huntingtons disease, which is one of the symptoms of the condition that is characterized by involuntary, jerky movements

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For most users, the greater weight loss more than justifies the additional GI management required

For example, studies have identified genes such as brain-derived neurotrophic factor (BDNF) and the serotonin transporter gene (SLC6A4) as being closely associated with depression susceptibility [292,293,294]

It names prior nausea disorders, gastroparesis risk, and renal impairment as raising heightened tolerability concerns