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5e, loss of HNF4 in HepG2 cells significantly changed the abundance of 65 metabolites (Supplementary Table 2, p 1.5), whereas the abundances of 174 metabolites were significantly different between control HepG2 and SNU449 cells (Supplementary Table 1)

From there the Harding lab built a series of metabolically stabilized angiotensin IV analogs, including an antagonist called Norleual, before arriving at dihexa, a stable, brain-penetrant descendant engineered to last in the body and reach the brain

Available: [Accessed: 16-May-2019]

5.2.1 F1 generation effects (direct offspring) The F1 generation, developing during EED exposure, exhibits the most severe reproductive impairments

The Liposomal Upgrade: Protection and Delivery To overcome these gastrointestinal limitations, scientists turned to liposomes