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If a patient returns to the sun after treatment, the discoloration and hyperpigmentation can easily recur

Comparison to Other Routes Intravenous: 100% bioavailability (by definitionthe full dose enters circulation) Subcutaneous: Likely 6090% bioavailability (depends on absorption rate) Oral: ~38% systemic bioavailability This is why some researchers hypothetically prefer injected routeshigher bioavailability means lower nominal doses are needed

Since GLP-1 agonists already reduce hunger and slow stomach emptying, adding a fasting protocol can amplify appetite suppression and create longer periods without food intake

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