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It's also possible that GLP- 1 affects cells indirectly

doi: 10.1016/j.genrep.2020.100608 28 ChristensenNJHabekostGBratholmP

A 2-year randomized controlled trial with low-dose B-vitamin supplementation shows benefits on bone mineral density in adults with lower B12 status

The compound can be used by women, though effects specific to female physiology have not been specifically studied

Conversion of calcidiol to its biologically active form, calcitriol, occurs through the activity of a specific 25-hydroxyvitamin D 3 1--hydroxylase (commonly just called 1--hydroxylase) present in the inner mitochondrial membrane of cells of the proximal convoluted tubules of the kidneys, and in several extrarenal sites such as in keratinocytes, macrophages, and placenta