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1 Moreover, the high failure rate of clinical trials makes it difficult to effectively validate hypotheses, possibly attributed to the coexistence of multiple theories (which will be detailed in subsequent sections)

Glycyrrhizin shows significant reduction in the degree of ferroptosis and inhibits OxS and provides anti-ferroptotic liver protection through up-regulation of Nrf2, HO-1 and Gpx4

Such benefits may be especially important for PWH, who frequently experience an accelerated aging phenotype driven by chronic immune activation and metabolic dysregulation 13

Another clinical trial found that individuals who shifted their dinner to an earlier time and avoided late-night eating lost more weight and reported reduced cravings

No specific study is named