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This review will focus on recent findings describing how different pathological states compromise BBB integrity, discuss current potential therapeutic approaches that have been explored for improving BBB integrity and slowing neurodegenerative disease pathologies, and the recent findings in microbial mediated modulation of the BBB

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Bruker Biospin MRI, Ettlingen, Germany), using a custom-built 1 H/ 2 H birdcage radiofrequency (RF) coil (Larmor Device, Hangzhou, China) [35] as receiver and transmitter