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The primary contraindications are a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 (MEN2) based on thyroid C-cell tumor findings in rodent studies at suprapharmacologic doses, with no established causation in humans at clinical doses but a sufficient concern for the contraindication to stand

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It's important to note that Ozempic and Wegovy have different delivery systems