Even in healthy athletes, the build-up of ammonia can lead to extreme fatigue and dementia because it reduces glycogen formation and inhibits the energy cycle
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Jha V, Garcia-Garcia G, Iseki K, Li Z, Naicker S, Plattner B, Saran R, Wang AY-M, Yang C-W (2013) Chronic kidney disease: global dimension and perspectives
Neuropsychiatric monitoring is particularly important: Mood changes : Report any worsening depression, increased anxiety, or suicidal thoughts immediately Sleep disturbances : Both medications can affect sleep patterns Fatigue or dizziness : May impair ability to drive or operate machinery Serotonin syndrome : A rare but serious condition associated with SSRIs, especially when combined with other serotonergic medications (not related to semaglutide) Metabolic and other considerations : Blood glucose effects : Wegovy can affect blood glucose levels