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Given the composite nature of bone tissue and the intricate requirements of bone tissue engineering materials, composite materials have become the preferred choice, offering superior performance compared to single-component materials ( Polymethyl methacrylate (PMMA) bone cement is extensively used in orthopedic surgery, but the high elastic modulus and low biocompatibility have limited further advancements (Zhu et al., 2020

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was supported by grants from the National Key Research and Development Program of China (2019YFA0508500), the National Natural Science Foundation of China (81821001, 82130107, 82330052) and the CAS Project for Young Scientists in Basic Research (YSBR-074)