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, Yoshino, J

While the prescribing information for GLP-1 medications does not specifically list Crohn's disease as a contraindication, the Summary of Product Characteristics (SmPC) for these medicines does advise caution in patients with gastrointestinal disease and states they are not recommended in severe gastrointestinal disease

Harlan Krumholz, a cardiologist and professor at Yale School of Medicine who wasnt involved in the study

Real-world registries and clinical trials have not identified semaglutide or tirzepatide as direct seizure triggers in people with well-controlled epilepsy

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