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Glutamate dehydrogenase and glutamate production The evidence that glutamate may serve as a second messenger to amplify insulin secretion comes from identifying a gain-of-function mutation in the gene encoding glutamate dehydrogenase (GDH), an enzyme that catalyses conversion of -ketoglutarate to glutamate

However, all observed effects derive from animal models and in vitro research systems

10.1111/j.1365-4632.2004.02389.x 211 YangY.DuY.CuiB

If a melanoma is confirmed another operation is usually required, most often performed by a plastic surgeon or dermatologist to remove a wider area of skin

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