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The wide range reflects how much technique matters

J Autoimmun 108:102402 Li L, Wang X, Sharvan R, Gao J, Qu S (2017) Berberine could inhibit thyroid carcinoma cells by inducing mitochondrial apoptosis, G0/G1 cell cycle arrest and suppressing migration via PI3K-AKT and MAPK signaling pathways

[vii] Davinelli S, Nielsen M, Scapagnini G, Astaxanthin in Skin Health, Repair, and Disease: A Comprehenisve Review, Nutrients 2018 April;10(4): 522 [viii]Giardi M, Touloupakis E, Bertolotto D, Mascetti G, International Journal of Molecular Sciences 2013 Aug

But which one should you choose

121 Treatment with CRMs has been found to decrease the concentration of free IGF-1, promote autophagy in cancer cells, and improve the antitumor immune response, resulting in a reduction in tumor growth when combined with immunogenic chemotherapeutics