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But retatrutide (LY3437943) backed up the hype with numbers no obesity drug has matched: 24.2% average body weight reduction at the highest dose in just 48 weeks, published in the *New England Journal of Medicine* by Jastreboff et al

This assay measured the total semaglutide concentration and had a lower limit of quantification (LLOQ) of 0.7 nmol/L [22]

Unlike its injectable counterpart, the Wegovy pill offers the same benefits without the need for needles