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References Aarsland D et al (2021) Parkinson disease-associated cognitive impairment

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Lidocaine stabilizes excitable membranes by reversible blockade of voltage-gated fast sodium channels in their open and inactivated states, thereby reducing the rate of phase 0 depolarization and suppressing spontaneous impulse generation in ectopic foci

Chronic hives may be treated with antihistamines or a combination of medications

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