The most common side effects are gastrointestinal, including nausea, vomiting, diarrhoea, and constipation
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"Growth Hormone and Aging." Endocrine Reviews , 2008
While this is not a source of iron toxicity, it still has an extremely damaging effect
Sitagliptin, anagliptin, gemigliptin, and teneligliptin form class 3 of the DPP-4 inhibitors (see Figure 2) ( Figure 2 The clinically most relevant and important action of DPP-4 inhibitors is the endogenous elevation of the incretin hormone concentration of GLP-1 that consecutively leads to a glucose-dependent stimulation of insulin secretion and an inhibition of glucagon secretion ( This article gives an overview on the characteristics of the various DPP-4 inhibitors in clinical use and highlights the positioning of the drug class in the guidelines for the treatment of type 2 diabetes