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Many phenolic acids are also known to suppress the NF-B pathway, thereby reducing pro-inflammatory cytokines in the tumor microenvironment and sensitizing cancer cells to immune attack (150)

In contrast, Schirmer I test values showed significant positive correlations with a broad panel of cytokines, including IFN-2 ( = 0.837

Furthermore, the negative association between low PRL levels, obesity, gluco-insulinemic and lipid impairment have also been observed in non-hyperprolactinemic subjects, thus leading to the hypothesis that PRL investigation should be offered also to obese or diabetic patients, besides those with suspicion of hyperprolactinemia

doi: 10.1007/s12035-022-02990-5, PMID: [DOI] [PubMed] [Google Scholar] 146