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Pharmacol Rev 54:101127 Talebi S, Bolhassani A, Azad TM, Arashkia A, Modaresi MH (2017) Immuno-stimulating peptide derived from HMGB1 is more effective than the N-terminal domain of Gp96 as an endogenous adjuvant for improvement of protein vaccines

The US Anti-Doping Agency (ADA) states that because it has not been extensively studied in humans, "no-one knows if there is a safe dose, or if there is any way to use this compound safely to treat specific medical conditions"

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doi: 10.1097/SHK.0000000000000320 106