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A minimal model was used for analyses in which there were insufficient numbers of eligible patients to allow use of the full model (see Exploratory Analyses: Impact of Baseline BMI, Demaglutide Dose, Previous Treatment, Sex and Age)

And while men may tolerate or even thrive on very low-carb diets due to differences in hormonal sensitivity, women are more likely to feel the hormonal ripple effects

Chronic elevation (hypercortisolism or Cushing's syndrome) leads to central obesity, insulin resistance, hypertension, muscle weakness (particularly proximal), wide purple striae, facial plethora, and increased cardiovascular risk

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